Rab11-fip1
WebJan 6, 2024 · Rab11-FIP1 depletion promotes epithelial cell disorganization and tumor cell invasion. Rab11-FIP1 regulates EMT through direct inhibition of Zeb1. Loss of the Rab … WebJan 6, 2024 · For Rab11-FIP1 knockdown studies, cells were infected with mouse lentiviral shRNAs against Rab11-FIP1 (Sigma, sequences are listed in Table 1) or non-targeting …
Rab11-fip1
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WebThe Rab11 Effector Protein FIP1 Regulates Adiponectin Trafficking and Secretion Brian P. Carson1¤a ☯, Josep Maria Del Bas1¤b, Jose Maria Moreno-Navarrete2, Jose Manuel Fernandez- Real2, Silvia Mora1* 1 Department of Cellular and Molecular Physiology, Institute of Translational Medicine, the University of Liverpool, Liverpool, United Kingdom, 2 Section … Proteins of the large Rab GTPase family (see for example RAB1A) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP1 is one of many proteins that interact with and regulate Rab GTPases. RAB11FIP1 has been identified as a novel protein involved in the … See more Rab11 family-interacting protein 1 (Rab11-FIP1) also known as Rab-coupling protein is a protein that in humans is encoded by the RAB11FIP1 gene. See more RAB11FIP1 has been shown to interact with RAB11A and RAB4A. See more • Wallace DM, Lindsay AJ, Hendrick AG, McCaffrey MW (2002). "The novel Rab11-FIP/Rip/RCP family of proteins displays extensive homo- and … See more
WebshRNA sequences correspond to Rab11-FIP1 siRNA Gene Silencer sequences After transduction, stable cell lines expressing the shRNA may be isolated via selection with puromycin Biosafety - Lentiviral Particles are replication-incompetent and are designed to self-inactivate after transduction and integration of shRNA constructs into genomic DNA … WebSep 28, 2024 · Moreover, Rab11-FIP1 and Rab11-FIP5 knockdown exhibited more significant inhibitory effects on pIgA transcytosis in incompletely polarized cells than in …
WebThe protein Rab11-FIP1/RCP, or alternatively named Rab11 family-interacting protein 1, or Rab-coupling protein, and encoded by the human gene RAB11FIP1/RCP is an effector … WebJan 6, 2024 · Loss of Rab11-FIP1 increases tumor cell invasion in part through mutant p53 but also in an independent manner. Furthermore, loss of Rab11-FIP1 in human ESCC cell …
WebRab11 family proteins consist of closely related Rab11a, Rab11b, and Rab25. They are small GTPases thought to play an essential role in regulating endocytic membrane traffic (1,2). …
WebPhosphorylation of Rab11-FIP1 persists through calcium switch and remains high after polarity has been reestablished whereas FIP2 phosphorylation is highest early in … blackmer picayuneWebAfter DSS treatment followed by a 24-hour-recovery period, Rab11-FIP1 KO mice showed greater body weight loss and more severe colonic mucosal damage than in heterozygous … garages earlstonWebOct 19, 2001 · MDCK localization of Rab11a with Rab11-FIP1, Rab11-FIP2, and pp75/Rip11.A–C, Rab11-FIP1, Rab11-FIP2, or pp75/Rip11 immunostaining is shown in the far left column. GFP-Rab11a and immunostaining for the junctional marker ZO1 are as indicated. A, cells were not treated.B, cells were treated with nocodazole. C, cells were … blackmer pump assembly